The A. Phex Brothers (エイ・フェックス兄弟 Ei Fekkusu-kyōdai) are minor antagonists featured in JoJolion.

The twin brothers are Rock Humans belonging to the Rokakaka Organization as assassins. They hunt down Karera Sakunami for her knowledge concerning the Rokakaka and clash with Josuke Higashikata. They are both Stand Users who wield their Schott Key No.1 and Schott Key No.2 in unison. Besides the elder brother's damaged right hand, both are identical in appearance and attire. The pair share a duality described as harmonious with one another, being based on the Japanese concept of “A-un”, which explains the connected nature of opposites and their seemingly contradictory similarities.