Renée of France

Renée of France (25 October 1510 – 12 June 1574), was the Duchess of Ferrara from 31 October 1534 until 3 October 1559 due to her marriage to Ercole II d'Este, grandson of Pope Alexander VI. She was the younger surviving child of Louis XII of France and Anne of Brittany. In her later life she became an important supporter of the Protestant Reformation and ally of John Calvin.